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Article #164: The Health Hazards of Smoking

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One of the biggest problems facing our expected results. The final piece of
world today is smoking, or more supportive data states that "Smokers
specifically smoking tobacco. Study of tended to have a greater reduction in VC,
the respiratory system and the effects of FVC, and FEV1/FVC relative to nonsmokers
smoking on the respiratory system is one and an elevated RV/TLC ratio". All of
of the examined health issues in our day. these previous experiments clearly
Emphysema, many different cancers, birth support the hypotheses stated in this
defects, and other severe lung problems laboratory experiment report, except for
are the result of smoking or other FVC which shouldn't be affected by
tobacco products. tobacco smoke according to this support
The question posed by this laboratory data, this information goes against what
experiment is to see the affects of was previously hypothesized for the
smoking related to immediate pulmonary affects of smoking on FVC values.
functions on young adults. The data was gathered using a spirometer
The direct inhalation of tobacco smoke connected via Powerlab software and
occurs first at the mouth, the smoke measured a broad range of pulmonary
travels down the trachea, through the functions.
bronchi to each lung, then down to the Materials and Methods:
bronchioles and into the alveolar and This experiment was preformed to examine
alveoli. The alveoli are where the the lung volumes and capacities, and many
greatest destruction is caused by tobacco other pulmonary functions. The experiment
smoke. was conducted on the students from all
This experiment is a perfect opportunity sections of biology 153 at the University
to study the affects of smoking on young of Kentucky. A spirometry test was
adults in particular, and tobacco's preformed while at rest and after
initial health effects on the user. If exercise, all data was collected with
smoking is directly related to a decrease Powerlab software. All data was
in pulmonary function, then people who correlated and compiled using Microsoft
smoke more than one pack a week or heavy Excel. This data should be relatively
smokers will show a dramatic difference precise given that it was all gathered
in pulmonary measurements such as vital and collected by computer software.
capacity (VC), functional residual Procedures were followed as prescribed by
capacity (FRC), forced vital capacity the respiration bulletin-experimental
(FVC), and the ratio of forced expired guide.
volume in one second (FEV1) to forced As detailed previously many pulmonary
vital capacity (FEV1/FVC), Compared to functions were tested and correlated
mild-smokers (less than or equal to one using data gathered by the spirometer,
pack of cigarettes per week) or and Powerlab software. It effectively
non-smokers. These will be the hypotheses measured all of the values that are to be
tested in this lab report. If smoking examined in this lab report (FVC, VC, and
does in fact affect these pulmonary FEV1/FVC ratio). FRC was calculated using
functions then there will be a noticeable information gathered by the spirometer.
difference in these values between the The level of treatment in this experiment
heavy smokers, mild-smokers, and was the amount of smoking. The three
non-smokers. categories included level 1 (heavy
The expected results of these tests would smokers) and is indicated by the
be anticipated to yield a great consumption of more than one pack per
difference in the pulmonary functions to week, level 2 (mild smokers) who consume
be tested among the groups of less than but up to one pack per week,
individuals. Greater differences among and level 3 (non-smokers) which consume
these results should be present in the zero cigarettes per week.
data for after exercise was preformed in The data was not replicated among
the group of smokers. individuals but was replicated 62 times
A previous study indicated that "Abnormal over the entire Bio 153 department among
spirometry (i.e., limitation of the students; two measurements of
expiratory airflow, airways obstruction, pulmonary function were conducted on each
or a low FEV1/FVC ratio the degree of student that preformed the test once at
airways obstruction correlates closely rest and once after exercise. The control
with pathologic changes in the lungs of group for this experiment was the
smokers and patients with COPD (Chronic non-smoker group, since they should have
Obstructive Pulmonary Disease)". This normal and unaltered pulmonary functions,
provides more evidenced that the tests given that none of the students measured
should provide noticeable differences in have any restrictive or obstructive
the FEV1/FVC ratio. Another study disorders.
specifies that "smokers, ex-smokers, and The population studied contained 62
never-smokers had similar FVC and static individuals, 36 females and 26 males. 34
lung volumes". Which indicates this lab non-smokers, 19 heavy smokers, and 5 mild
report should not yield any differences smokers, this population size and
in FVC values between the groups of characteristics were sufficient for the
individuals studied. An alternative study experiment conducted. Data was correlated
also suggested that "mean FRC and RV were into their respective groups and measured
higher of smokers had a significantly for each of the values to be tested;
reduced FEV1" (Clark et al. 2001). This graphs were used to make it easy to see
provides more support for the hypotheses immediate differences among the group's
presented in this lab report will yield variables.






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