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Article #505: Antioxidants And Brain Health

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Your brain is your greatest asset but it radicals.
is also your body's most vulnerable Benefits of Dietary Antioxidants
organ. It requires constant support from What safeguards can healthy people take
other major organs and is your most to reduce risk of diseases and especially
susceptible organ to oxidative stress to protect their brains from oxidative
during aging. stress over a lifetime?
Here are some brain facts: The simplest answer is to follow a diet
1. Your brain makes up only 2% of your that includes abundant sources of
total body weight but requires 20% of antioxidant chemicals derived from plant
your heart's output of blood to sustain foods. Evidence for the benefits of such
the amount of oxygen that it needs. a dietary regimen has only been
2. Your brain is the most demonstrated in experiments with animals
oxygen-demanding organ in your body. up until now, but the results are
3. Your brain uses chemicals convincing. Over the past eight years,
(neurotransmitters) to relay important the research activities of Dr. Jim Joseph
messages to other parts of your body. of the US Department of Agriculture,
These same chemicals are also involved in Boston, have focused on how to protect
chemical reactions that produce damaging the brain from oxidative stress with
free radicals. dietary use of antioxidant-rich plants
4. If your brain cells become weak or die such as strawberries, cranberries,
they cannot repair themselves. Their elderberries, blueberries and spinach.
functions then can be permanently lost if Dr. Joseph's research findings-a message
cell death or damage occurs. closely pertinent to this essay-can best
Given these susceptibilities, your brain be represented by a quote from one of his
is especially vulnerable to conditions research reports in 1998: "increased
that threaten oxygen supply, such as in antioxidant protection through diets
head injury, stroke, lung diseases and comprised of fruits and vegetables
heart failure. Under these conditions, identified as being high in total
brain activity will continue even without antioxidant activity might prevent or
enough oxygen. This can cause problems reverse the deleterious effects of
that lead to extreme levels of oxidative oxidative stress on neurons."
stress and the over-production of Summary: Oxidative stress is a major
damaging free radicals. factor in brain aging. This stress can be
In diseases like Alzheimer's and combated or balanced by including dietary
Parkinson's, other damaging factors are antioxidants into your daily life. The
at work. In Alzheimer's disease, a toxic best way to do this is by eating lots of
protein called beta-amyloid, forms in colorful fruits and vegetables each day.
your brain tissue. This protein acts as Reading
an irritant and causes inflammation in * Lau FC, Shukitt-Hale B, Joseph JA. The
your brain. This inflammation then causes beneficial effects of fruit polyphenols
the production of free radicals that can on brain aging. Neurobiol Aging. 2005
destroy any membranes and cells in their Dec;26 Suppl 1:128-32.
path. * Joseph JA, Shukitt-Hale B, Denisova NA,
Parkinson's disease results from Prior RL, Cao G, Martin A, Taglialatela
unregulated production of the brain G, Bickford PC. Long-term dietary
chemical dopamine which, with the help of strawberry, spinach, or vitamin E
free radicals, becomes toxic to the brain supplementation retards the onset of
cells that control your motor functions. age-related neuronal signal-transduction
Even in a healthy brain, oxygen radicals and cognitive behavioral deficits.
are produced every moment during normal J Neurosci. 1998 Oct 1;18(19):8047-55.
high-oxygen demand of neuronal activity. * Joseph JA, Nadeau DA, Underwood A. The
In a healthy brain, enzymes and Color Code. Hyperion, New York, 2002.
nutritional antioxidants neutralize these Copyright 2006 Berry Health Inc.






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